Cortical and trabecular morphometric properties of the human calvarium

There is currently a gap in the literature that quantitatively describes complex bone microarchitecture within diploë (trabecular bone) and cortical layers of human calvarium. The purpose this study was to determine morphometric properties tables calvarium which key interacting factors sex, location on calvarium, sandwich structure were considered. Micro-computed tomography (micro-CT) utilized capture images at 18 μm resolution male (n = 26) female 24) embalmed specimens frontal parietal regions (N 50). All post-processed analyzed using vendor bundled CT-Analyzer software layers. A two-way mixed (repeated measures) analysis variance (ANOVA) used accounting for sex location. three-way ANOVA performed layer (inner outer table), revealed no interaction effects between morphometry except fractal dimension. Trabecular thickness separation significantly greater specimens; however, females showed number trabeculae dimension average. Parietal porosity, trabecular separation, deviation from an ideal plate structure, but lesser connectivity compared Additionally, observed lower density porosity inner than may be due clear distinctions each layer's physiological environment. provides valuable insight into quantitative finite element modelers skull can refer when designing detailed heterogenous or subject-specific models effectively predict injury. Furthermore, contributes towards recent developments physical surrogate require approximate measures architecture order fabricate model then accurately simulate traumatic head impact event.